The quarterly scientific journal

Increasing biologics manufacturing capacities

With 23+ years of experience handling hundreds of cell and virus models, Clean Cells has positioned itself as a leader in cell and virus banking, providing complementary characterization and storage services. Our state-of-the-art cGMP facility launched earlier this year now welcomes our biologics manufacturing capacities, providing 8 new clean rooms designed for all types of biopharma projects and equiped to meet production specifications for both adherent and suspension cells.

Assessing the scale-X(TM) bioreactor’s biomanufacturing capacities on Vero cells

To further extend their biomanufacturing capabilities and cater to Univercells clients' growing needs, Naobios has recently conducted a comprehensive assessment of the performance of Vero cells cultured within the scale-X(TM) bioreactor provided by Univercells Technologies. This assessment aimed to evaluate the compatibility and efficiency of the Vero cell line in this novel bioreactor system for viral-based bioproduction.

A new facility to extend biopharma services

• Biosafety testing
• cell banks
• end-to-end
• Facilities
• Testing
• virus banks

Last January, Clean Cells opened its new cGMP-compliant facility, a cutting-edge 5 300 m2 platform which considerably extends biopharma capacities. Additional biologics testing capacity, extended cell and gene therapy services, end-to-end biomanufacturing and storage: Clean Cells’ new site opens a new chapter in the company’s rich history.

Characterization and control testing of lentiviral vectors and derived products

• Gene Therapy
• lentiviral vectors
• RCL Pool assay

Clean Cells has partnered with customers on dozens of gene therapy projectsinvolving testing of lentiviral vectors and CAR-T cell therapies.

Integrated solution for cell banking and characterization

• Cell banking
• Characterization
• Master Cell Banks
• MCB
• Storage

Clean Cells offers an integrated solution for cell bank generation in GMP and non-GMP-settings together with full characterization services and additional long-term storage options to secure valuable material.

GMP biomanufacturing in a BSL-3 suite

• BSL3
• Capabilities
• Facilities
• manufacturing

A GMP biomanufacturing expert, Naobios has worked with numerous viruses requiring specific biocontainment procedures. Our state-of-the-art BSL-3 suite welcomes hazardous microbes used for the generation of virus-based therapeutic products.

Optimization and Validation of digital PCR assays

• analytical development
• assays
• digital PCR
• dPCR
• PCR
• QC
• quality control

Following the implementation and qualification of a digital PCR platform, Clean Cells has completed optimization and validation work according to ICHQ2(R1) and 21CFR part 11 to support internal methods and culminating in full GMP compliance.